江苏省35～74岁人群代谢综合征的流行病学调查

Study on the prevalence of metabolic syndrome among 35-74 year-olds in Jiangsu province

目的调查江苏省人群代谢综合征(MS)的流行现况,初步评估不同定义在中国人群中的运用价值。方法采用多级分层整群抽样的流行病学调查的方法进行问卷调查,有效调查人数为5888人,对全部样本人群(5888人)测定空腹血糖、血脂、体重指数、血压等,运用IDF(2005)和ATPⅢ(2005)的MS定义对资料进行分析。结果①江苏省社区人群MS的患病率分别为17．48％[IDF (2005)]和21．95％[ATPⅢ(2005)],女性显著高于男性(P<0．01);②随着年龄增加,MS患病率升高,特别是50岁以上女性人群患病率升高更明显;③不同教育程度、婚姻情况、职业间MS患病率显著不同;④城市MS患病率显著高于农村,且苏南地区MS患病率显著高于苏北;⑤MS中最多见的表现形式是中心性肥胖+血脂异常+高血压和中心性肥胖+血脂异常+高血压+高血糖。结论江苏省社区人群具有很高的MS患病率,且多种代谢异常的聚集较为严重;由于MS存在种族差异,该项研究认为MS定义中中国人群腰围截断值的适宜切点可能还需探讨,结合人群MS的特点,选择适合于中国人群的MS诊断标准,将更有利于临床应用、MS的防治及降低心血管疾病的发生。

Objective To describe the prevalence of metabolic syndrome （MS） in Jiangsu province, using IDF 2005 and ATPⅢ 2005 definition. Methods Multistage cluster sampling method was used and the participants were interviewed by trained health workers under a structured questionnaire. The number of research subjects was 5888. Fasting plasma glucose（FPG）, blood lipids, body mass index, blood pressure （BP） of all sample population （5888 subjects） were measured. Results The prevalence of MS was 17.48% by IDF 2005 definition and 21.95% by ATPⅢ 2005 definition. Women had higher prevalence than men （ P 〈 0.01 ）. The prevalence of MS increased with age. Abrupt increase of the prevalence started at age of 50 in women. The prevalence varied by education, marital status, occupation and income. People from the urban and the south had a higher prevalence than from the rural and from the northern part of the country. The most common combination of MS individual components were 1 ） central obesity, dislipidemia and high BP; 2） central obesity, dislipidemia, high BP and high FPG. Conclusion The prevalence of MS was high in Jiangsu province. Clustering of MS components was common. It is necessary to discuss the cutoff points of central obesity for the waist circumference diagnostic criteria of MS in Chinese population. The importance of prevention of MS should be strengthened both by health professionals and the government.