类风湿性关节炎对绝经后妇女骨质疏松的影响

Affection of rheumatoid disease on female teoporosis

目的了解类风湿性关节炎（RA）患者骨密度（BMD）的变化和骨质疏松（OP）的发生情况。 方法采用双能X线骨密度仪（DEXA）对40例55～70yr的RA绝经女性患者和60例正常健康绝经女性进行腰椎（L1-4）、左股骨上端（股骨颈、Ward’s三角区、大转子）BMD测定，所得数据进行统计分析。 结果RA组无论腰椎或股骨上端的骨量丢失均较健康对照组有显著性差异（P〈0．05），RA患者BMD明显低于健康对照组，OP患病率达85％。 结论RA患者存在着明显的骨质丢失情况。

Aim To evaluate the changes of bone mineral density and incidence of osteoporosis among patients with rheumatoid arthritis . Methods A total of 100 postmenopausal women were enrolled into the study, among whom 40 were with RA and 60 healthy. Every case received DEXA at different locations （lumbar vertebra, hip ）.The BMD and incidence of osteoporosis were compared between groups. Results The BMD of RA group significantly decreased at both lumbar and hip. There was evident difference between the groups in the incidence of osteoporosis, while the incidence of osteoporosis in RA was obviously higher . Conclusion RA can lead to significant bone loss in postmenopausal patients, and even in healthy postmenopausal women, osteoporosis is also common .