小鼠树突状细胞亚群与T细胞关系的研究进展

Advances in Research on the Relationship between Murine Dendritic Cell Subsets and T Cells

树突状细胞(dendritic cells,DCs)是目前已知机体内功能最强的专职性抗原提呈细胞,其最大特点是能够显著刺激初始型T细胞(naive T cells)增殖,是机体免疫反应的始动者。近年来,随着对小鼠DCs研究的不断深入开展,本文在此对DCs亚群与T细胞之间相互关系的研究取得的进展综述如下。

It is generally accepted that dendritic cells are the most powerful professional antigen-presenting cells in vivo. They play a major role in the induction of primary immune responses. The most important feature of those cells is to activate naive T cells to proliferate dramatically. In recent years, rapid progress in research on murine dendritic cells has been acquired. This article will review the significant advances in understanding the relationship between murine dendritic cell subsets and T cells.