中西医结合防治心肌纤维化的研究进展

Progress in Integrative Chinese and Western Medicine Study on Prevention and Treatment of Myocardial Fibrosis

心肌纤维化是冠心病、心肌梗死、高血压、心肌病等多种常见心脏疾病向终末期心脏病发展的一个必然过程,阻止或逆转纤维化是延缓心力衰竭、减少心律失常发生的重要手段。中医学可将心肌间质纤维化归属于“心痹”范畴。文章就心肌纤维化的发生、调控、中西医结合辨治、单味中药及成分的研究作一综述。

Myocardial fibrosis is an inevitable process of many heart diseases, such as coronary heart disease, myocardial infarction, hypertension, cardiomyopathy, etc. in development from earlier period to terminal stage. To prevent or reverse the process of fibrosis is one of the most important approaches to retard the occurrence of heart failure and reduce the accidence of arrhythmia. In traditional Chinese medicine myocardial fibrosis belongs to the category of “Xinbi”. Studies on the occurrence and regulation of myocardial fibrosis, and its treatment by using integrative Chinese and Western medicine or by Chinese drugs singly and their components were reviewed in this paper.