印度南部农村地区闭角型青光眼的患病率

Prevalence of angle-closure disease in a rural southern Indian population

Objective:To estimate the prevalence of primary angle-closure glaucoma,primary angle closure(PAC),and primary angleclosure suspect(PACS)and its associated risk factors in a rural population in southern India.Methods:Three thousand and nine hundred thirty-four(81.95%)of 4800 enumerated subjects aged 40 years or older underwent a complete ophthalmic examination,including compression gonioscopy.Glaucoma was diagnosed using International Society of Geographical and Epidemiological Ophthalmology classification.Results:Data were analyzed for 3924 subjects(81.75%).Primary angleclosure glaucoma was diagnosed in 34 subjects(0.87% ;95% confidence interval CI,0.58 to 1.16)(27 women,7 men).The mean intraocular pressure was 20.71± 9.24 mm Hg.One subject(2.94%)was blind.Twenty-eight subjects(0.71% ;95% CI,0.45 to 0.98)were diagnosed to have PAC(21 women,7 men).Eleven subjects(39.3%)had an intraocular pressure greater than 21 mm Hg,13 subjects(46.43%)had peripheral anterior synechiae,and 4 subjects(14.29%)had both.Two hundred forty-six subjects(6.27% ;95% CI,5.51 to 7.03)had PACS(168 women,78 men).Primary angle closure and primary angle-closure glaucoma were more common in women(age-adjusted odds ratio,3.02;95% CI,1.66 to 5.51)with an increasing prevalence with age.Increasing intraocular pressure was associated with the disease(odds ratio,1.14;95% CI,1.09 to 1.19).There was no association with hypertension and hyperopia.Axial length and anterior chamber depth were longer in the normal group than in the 3 groups with angle closure(P <.05).Women had shorter axial lengths than men(P <.001)in the angle closure groups.Conclusions:The overall prevalence of primary angle closures(PAC and primary angleclosure glaucoma)in a rural population of southern India was 1.58%.There was a female preponderance,and the disease tends to be asymptomatic.

Objective： To estimate the prevalence of primary angle-closure glaucoma, primary angle closure （PAC）, and primary angleclosure suspect （PACS） and its associated risk factors in a rural population in southern India. Methods： Three thousand and nine hundred thirty-four （81.95%） of 4800 enumerated subjects aged 40 years or older underwent a complete ophthalmic examination, including compression gonioscopy. Glaucoma was using International Society of logical Ophthalmology classifi analyzed for 3924 subjects （ diagnosed Geographical and Epidemiocation. Results： Data were 81.75% ） . Primary angleclosure glaucoma was diagnosed in 34 subjects （0. 87% ; 95% confidence interval [CI], 0.58 to 1.16） （27 women, 7 men） The mean intraocular pressure was 20. 71 ＋9.24 mm Hg. One subject （2. 94% ）was blind. Twenty-eight subjects （0.71%; 95% CI, 0.45 to 0.98） were diagnosed to have PAC （21 women, 7 men）. Eleven subjects （39. 3% ） had an intraocular pressure greater than 21 mm Hg, 13 subjects （46.43%） had peripheral anterior synechiae, and 4 subjects （14. 29% ） had both. Two hundred forty-six subjects （6.27% ; 95% CI, 5.51 to 7.03） had PACS （168 women, 78 men） . Primary angle closure and primary angle-closure glaucoma were more common in women （age-adjusted odds ratio, 3.02; 95% CI, 1.66 to 5.51） with an increasing prevalence with age. Increasing intraocular pressure was associated with the disease （odds ratio. 1.14; 95% CI, 1.09 to 1.19） . There was no association with hypertension and hyperopia. Axial length and anterior chamber depth were longer in the normal group than in the 3 groups with angle closure （P 〈0. 05） . Women had shorter axial lengths than men （P 〈0. 001） in the angle closure groups. Conclusions： The overall prevalence of primary angle closures （PAC and primary angleclosure glaucoma） in a rural population of southern India was 1.58%. There was a female preponderance, and the disease tends to be asymptomatic.