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造血干细胞移植治疗难治性类风湿关节炎 被引量:3

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摘要 类风湿关节炎(rheumatoid arthritis,RA)是一种以关节滑膜炎为主要特征的慢性自身免疫性疾病(AD),全世界的患病率大约为1%,我国该病患病率为0.32%~0.36%,患病总人数至少400万。此病是造成我国人群丧失劳动力和致残的主要病因之一。传统的治疗方案能控制大部分的病例.但难治性RA发病快、病死率高,对传统治疗方法反应较差。近年来造血干细胞移植(hematopoietie stem cell transplantation.HSCT)应用于难治性RA取得了令人鼓舞的疗效。
出处 《中华风湿病学杂志》 CAS CSCD 2006年第9期561-563,共3页 Chinese Journal of Rheumatology
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  • 1张乃峥.类风湿关节炎[A].见:张乃峥主编.临床风湿病学[C].上海:上海科学技术出版社,1999.118—137.
  • 2Baldwin JL,Storb R,Thomas ED,et al.Bone marrow transplantation in patients with gold -induced marrow aplasia.Arthritis Rheum,1977,20:1043-1048.
  • 3Morton JL,Siegel BV.Transplantation of autoimmune potential I development of antinuclear antibodies in H-2 histocompatible recipients of bone marrow from New Zealand black mice.Proc Natl Acad Sci USA,1974,71:2162-2165.
  • 4Ikehara S,Kawamura M,Takao F,et al.Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cells.Proc Natl Acad Sci USA,1990,87:8341-8344.
  • 5Ikehara S,Good RA,Nakamura T,et al.Rationale for bone marrow transplantation in the treatment of autoimmune diseases.Proc Natl Acad Sci USA,1985,82:2483-2487.
  • 6Knaan-Shanzer S,Houben P,Kinwel-Bohre EP,et al.Remission induction of adjuvant arthritis in rats by total body irradiation and autologous bone marrow transplantation.Bone Marrow Transplant,1991,8:333-338.
  • 7Matzinger P.The danger model:a renewed sense of self.Science,2002,296:301-305.
  • 8Medzhitov R,Janeway C Jr.Innate immunity.New Engl J Med,2000,343:338-344.
  • 9Openshaw H,Stuve O,Antel JP,et al.Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor.Neurology,2000,54:2147-2150.
  • 10Burt RK,Verda L,Oyama Y,et al.Non-myeloablative stem cell transplantation for autoimmune diseases.Springer Semin Immuno Pathol,2004,26:57-69.

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