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JAK/STAT信号转导通路与类风湿关节炎 被引量:12

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摘要 JAK/信号转导子和转录激活子(signal transducer and activator of transcription,STAT)信号途径是继Ras途径之后发现的又一重要的细胞因子信号转导通路。也是人体内生理和病理反应的共同通路之一,在调节机体炎症反应过程中发挥着极为重要的作用,研究类风湿关节炎(rheumatoid arthritis.RA)滑膜组织JAK/STAT信号转导途径有助于从一个新的角度探索滑膜细胞病变发生机制,从而为治疗RA提供新的作用靶点。
出处 《中华风湿病学杂志》 CAS CSCD 2006年第9期563-566,共4页 Chinese Journal of Rheumatology
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