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直线加速器放射外科治疗脑血管畸形的临床评价 被引量:1

Clinical evaluation of linear accelerator radiosurgery for intracrarual arteriovenous mal-formations
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摘要 报告采用立体定向放射外科方法治疗脑血管畸形30例。80%等剂量区的靶剂量设计为15~20Gy。在1~2年内畸形血管团完全及次全闭塞率为67%。1例放疗后6个月死于再出血,其余病人随访期间均未发现再出血。癫痫为首发症状者其控制率达81.8%。4例出现后期放疗反应,表现为较广泛的白质水肿,其中2例开颅手术,切除的畸形血管均已闭塞。本文就放射外科治疗后再出血、癫痫控制以及其他神经系统反应等有关问题进行讨论。 0 patients affected by cerebal arteriovenous malformations (AVMs) underwent rediosurgical treat-ment in our department from June. 1992 up to date. The leasion was irradiated 15-20Gy to the 80%isodose. 1-2 years control angiography was performed in 12 of 30 patientts. The complete aind subtotallobliteration rate was 67%. The controf rate of epilepsy was 81%. One patient died of rebleeding at 6months after treatment. Four patients suffered undue effects of irradiation and aniong them sugical re-moval were performed in two patients. Clinical date are available for other patients. In this article, theobliteration rate, bleeding risk, seizurse and other neurlolgical deficit rate dter radiosurgery are discussed.
出处 《功能性和立体定向神经外科杂志》 1996年第3期14-15,共2页
关键词 动静脉畸形 直线加速器 放射外科 脑血管畸形 Arteriovenous malformation, Linear accelerator, Muosurgery
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  • 1杨开军,刘承勇,任文德,许志新,杨雄浩.X-刀治疗的质量控制及相关物理参数的测量[J].功能性和立体定向神经外科杂志,1995,8(3):4-6. 被引量:14
  • 2Colomb F,Pozza F,Chiierego G,et al.Linear accelerator radiourgry of cererbral arteriovenous maltormatious:an update.Neurosurgery,1994,34(1):14-18
  • 3Karlsson B,Lindquist C,Steiner L.Effect of Gamma Knife surgery on the risk of rupture prior to AVM obliteration.Minim Invasive Neurosurg ery(Stattgart),1996,39(1):21-25
  • 4杨开军,刘勇,任文德,等.颅内疾病X刀治疗学[M].北京:人民卫生出版社,1997.133-138.

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