摘要
报告采用立体定向放射外科方法治疗脑血管畸形30例。80%等剂量区的靶剂量设计为15~20Gy。在1~2年内畸形血管团完全及次全闭塞率为67%。1例放疗后6个月死于再出血,其余病人随访期间均未发现再出血。癫痫为首发症状者其控制率达81.8%。4例出现后期放疗反应,表现为较广泛的白质水肿,其中2例开颅手术,切除的畸形血管均已闭塞。本文就放射外科治疗后再出血、癫痫控制以及其他神经系统反应等有关问题进行讨论。
0 patients affected by cerebal arteriovenous malformations (AVMs) underwent rediosurgical treat-ment in our department from June. 1992 up to date. The leasion was irradiated 15-20Gy to the 80%isodose. 1-2 years control angiography was performed in 12 of 30 patientts. The complete aind subtotallobliteration rate was 67%. The controf rate of epilepsy was 81%. One patient died of rebleeding at 6months after treatment. Four patients suffered undue effects of irradiation and aniong them sugical re-moval were performed in two patients. Clinical date are available for other patients. In this article, theobliteration rate, bleeding risk, seizurse and other neurlolgical deficit rate dter radiosurgery are discussed.