TPN的不同输入对围手术期老年胃癌患者血黏度的影响

The effect of TPN by different abminstered on blood viscosity in elderly patients with gastric cancer

目的观察TPN的不同输入对围手术期胃癌患者血黏度的影响。方法将60例病理证实的进展期胃癌患者分为三组,实验组1(G1):20%力能(LCT)提供30%非蛋白热卡;实验组2(G2):20%力能提供30%非蛋白热卡,8h内直接静脉输入;对照组(G3):葡萄糖提供100%非蛋白热卡。能量给予105kJ/kg·d,N0.12g/kg·d,G1和G3营养液以“全合一”液匀速输入。分别于营养前(术后)及营养后测定外周血血黏度和血乳糜微粒。结果G2组血黏度有升高但差异无统计学意义(P>0.05),血乳糜微粒明显升高(P<0.01)。G1和G3两组间差异无统计学意义(P>0.05)。结论力能脂肪乳提供30%非蛋白热卡对老年人血黏度无明显影响,但直接静脉输入血黏度有所升高,血乳糜微粒明显升高,对机体可能产生不利影响。

Objective The effect of TPN by different abminstered on blood viscosity in elderly patients with gastric cancer. Methods 60 patients were diagnosis of advanced gastric cancer s were divided into three groups. G1 ： 20 % lipovenoes provided 30 % nonprotein calories; G2 ： 20 % lipovenoes group provided 30% nonprotein calories by direct venous injection in 8 hour; G3：100% nonprotein calories were provided as glucose. Each groups received full feeding with 105 kJ（25 kcal）/kg, d,N 0.12 g/kg. d. G1 and G3 were adminstered intravenously over 16- 24 hours as＂all in one＂. Before and after nutrition,the blood viscosity and the blood chyle was determined. Result The result showed that the blood viscosity G2 after nutrition were trivial rose than before nutrition and other groups, but the blood chyle after nutrition was significantly rose in group2 than before nutrition and other groups. Conclusion Lipid emulsion provided 30 % nonprotein calories was not significantly effect in elderly patients with gastric cancer, but the the blood chyle after nutrition was significantly rose with lipid emulsion direct venous injection.