摘要
目的观察常规机械通气(CMV)治疗兔海水型肺水肿(PE-SWD)的效果。方法应用CMV对14只PE-SWD新西兰大白兔进行救治,观察治疗后血气分析、肺损伤指标、病理学的改善情况,并观察部分呼吸动力学、血流动力学指标。结果CMV通气治疗后PE-SWD兔动脉血氧分压(PaO2)、血氧饱和度(SaO2)、二氧化碳分压(PaCO2)均较未治疗组有明显改善(均P<0.01),呼吸动力学、血流动力学异常得到一定程度纠正,通气治疗后肺损伤程度减轻。结论CMV通气治疗PE-SWD时低氧血症效果满意。
Objective To observe the therapeutic effect of conventional mechanical ventilation （ CMV ） on pulmonary edema after seawater drowning in rabbits （ PE-SWD ）. Methods Fourteen seawater lavage induced pulmonary edema New Zealand rabbits models were randomly assigned to receive CMV treatment. Blood gas analysis, pulmodynamic, hemodynamics status were monitored. Results PaO2 and SaO2 were significantly increased after the use of ventilation in PE-SWD（ P 〈 0.01 ）. Pulmodynamic and hemodynamics situations were improved. The degrees of lung injury were relieved. Conclusion CMV can significantly improve hypoxemia of PE-SWD rabbits models.
出处
《中国综合临床》
北大核心
2006年第11期989-991,共3页
Clinical Medicine of China
关键词
肺水肿
海水淹溺
常规机械通气
Pulmonary edema
Seawater drowning
Conventional mechanical ventilation
