1Pegg AE. Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents [J] . Cancer Investigation, 1984, 2:223 - 231.
2McCarthy TV, Karran P, Lindahl T.Inducible repair of O9-alkylated DNA pyrimidines in Escherichia coli [J]. EMBO J, 1984, 3:545 - 550.
3Teo I, Sedgwick B, Demple B, et al.Induction of resistance to alkylating agents in E. coli: the ada + gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage [J]. EMBOJ, 1984,3(9):2151-2157.
4Scudiero DA, Meyer SA, Clatterbuck BE,et al. Sensitivity of human cell strains having different ability to repair O6-methylguanine in DNA to inactivation by alkylating agents including chloroethylnitrosourea [J]. Cancer Res, 1984, 44:2467 - 2474.
5Tsujimura T, Zhang Y, Fujio C, et al.O6-methylguanine-DNA methyltransferase activity and sensitivity of Japanese Tumor Cell Strains to ACNU [J]. Japan J Cancer Res, 1987, 78:1207 - 1215.
6Watatani M, Ikenaga M, Hatanaka T, et al. Analysis of MNNG-induced DNA damage in tumor cell strains from Japanese patients and demonstration of MNNG hypersensitivity of Mer- xenografts in athymic nude mice [J]. Carcinogenesis,1985, 6:549 - 553.
7Mattern J, Eichhorn U, Kaina B, et al.O6-methylguanine-DN A methyltransferase activity and sensitivity to cyclophosphamide and cisplatin in human lung tumor xenografts [J]. Int J Cancer, 1998, 77:919 -922.
8Piccioni D, D'Atri S, Papa G, et al.Cisplatin increases sensitivity of human leukemic blasts to triazene compounds [ J].J Chemother, 1995, 7(3): 224-229.
9Preuss I, Thust R, Kaina B. Protective effect of O6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs [J] .Int J Cancer,1996, 65(4): 506 -512.
10Chen SS, Citron M, Spiegel G, et al.O6-methylguanine-DNA methyltransferase in ovarian malignancy and its correlation with postoperative response to chemotherapy [J]. Genecol Oncol, 1994, 52(2): 172 - 174.