手法治疗实验性膝骨关节炎研究

Study on Treatment for Experimental Knee Osteoarthritis with Massage

为观察手法对骨关节炎的治疗作用，将新西兰大白兔１８只随机分为三组，Ａ组为对照组：Ｂ组为手法治疗组；Ｃ组为开窗治疗组。造模前及术后１２周作双侧膝旁骨内压测定，结扎右股静脉后及Ｃ组开窗减压前作骨内压测定；造模前、造模６周、１２周后各作血液流变学检测。结果显示：结扎股静脉及臀下静脉使右膝旁骨内压立即增高（Ｐ＜０．０１），并造成骨内持续高压，造模后全血粘度及血浆粘度升高（Ｐ＜０．０１）；手法治疗后膝旁骨内压明显下降（Ｐ＜０．０５），全血粘度下降非常显著（Ｐ＜０．０１）。表明：手法治疗能减轻骨内高压，降低异常的全血粘度，改善骨内血液循环。

In order to assess the effects of treatment of massage on osteoarthritis of knee joint,we randomized 18 New Zealand white rabbits into three groups: group A was control one, group B were subject for massage treatment,group C fenestrated for measurement of intraosseous pressure.The juxta-articular intraosseous pressure(IOP) of both knees were measured before operation and 12 weeks after operation。 The IOP were also measured after ligation of the femoral veins and fenestration in group C.Hemorheological measurement was taken before operation,6 and 12 weeks after operation respectively.It demonstrated that juxta-articular IOP raised right after ligation of both femoral vein and inferior gluteal vein(P<0.01),and remained at a high level.After opertion,the viscosities of all blood and plasma also raised(P<0.01). The juxta-articular IOP dropped markedly (P<0.05),the level of the blood viscosity was also lowered significantly(P<0.01). It indicated that the treatment of massage lowered the high level of IOP and reduced the blood viscosity which will improved the intraosseous blood circulation.