脐血必需元素含量与胎儿畸形的相关性研究

A CORRELATIVE RESEARCH BETWEEN ESSENTIAL ELEMENTS IN UMBILICAL CORD BLOOD AND FETALIS DEFORMANS

应用偏振塞曼原子吸收法测试１５５例脐血必需元素的含量。结果畸表儿组脐血锰（２４．５５±７．３４）μｇ／Ｌ；铁（３２８．５８±１１８．５０）ｍｇ／Ｌ；铜（０．６９±０．２９）ｍｇ／Ｌ；镁（３３．８９±８．８６）ｍｇ／Ｌ，正常体重儿组脐血锰（３１．１２±１１．６７）μｇ／Ｌ；铁（３７３．６８±９７．８０）ｍｇ／Ｌ；铜（０．５７±０．２０）ｍｇ／Ｌ；镁（３０．９２±６．５９）ｍｇ／Ｌ．畸形儿组脐血锰、铁含量明显低于正常体重儿组（Ｐ＜０．０１及Ｐ＜０．０５），而铜、镁含量高于正常体重儿组（Ｐ＜０．０１及Ｐ＜０．０５）。提示低锰、低铁与胎儿畸形关系非常密切，多种人体必需元素平衡失调与胎儿畸形有关。

Polarized Zeeman AAS was used to determine the essential elements in the umbilicalcord blood of 155 cases.The results are as follows:the deformed neonate group:Mn(24.55±7.34)μg/L,Fe(328.5±1118.50)mg/L,Cu(0.69±0.29)mg/L,Mg(33.89±8.86)mg/L,and the normal weight neonate group:Mn (31.12±11.67)μg/L,Fe(373.68±97.80)mg/L,Cu(0. 57±0.20)mg/L,Mg(30.92±6.59)mg/L.The contents of Mn and Fe in the umbilicalcord blood of the deformed neonate group were obviously less than those of the normal weightneonate group(P<0.01and P<0.05).But the contents of both Cu and Mg are higher in thedeformed group than thoes of the normal group(P<0.01 and P<0.05).This study suggeststhat low Mn and low Fe are closly related to fetus malformation,and the formation of fettis mal-formation is closely connected with the imbalance of these essential elements in the human body.