结肠癌肝转移灶同期切除后门静脉化疗

Port Vein Chemotherapy after Simultaneous Colorectal Cancer and Liver Metastasis Resection

目的观察结肠癌肝转移同期切除后门静脉化疗的疗效.方法对18例结肠癌并肝转移患者进行结肠肿瘤切除或根治性切除术和以肝转移灶为中心的不规则肝切除术,并进行术中和术后的门静脉化疗.结果18例中生存1 a者15例(83.3%),3 a者10例(55.6%).结论对结肠癌伴有肝转移的患者同期行根治术及不规则肝切除术后,采用术中术后门静脉插管化疗,可明显提高肝转移癌的疗效,延长生存期.

Objective To evaluate the efficacy of port vein chemotherapy after simultaneous colorectal and liver resection. Methods 18 patients underwent carcinoectomy operation of colon or radical colorectal resection and irregular resection of hepatic metastases simultaneously in a single operation, and were given port vein chemotherapy in and after the operation. Result The survival rate at 1 year and 3 year were 83.3% and 55.6% respectively. Conclusion Patients underwent simultaneously colorectal and liver metastasis resection, port vein chemotherapy can improve response rate and prolong median survival to hepatic metastases of colorectal cancer.