摘要
干扰素是由多种细胞产生的可溶性糖蛋白,具有广泛的抗病毒、抗肿瘤和免疫调节作用。但是越来越多的实验结果表明干扰素在哺乳动物胚胎植入子宫、怀孕的维持以及早期胚胎发育中发挥着重要作用。结合本实验室的研究工作对干扰素的作用机制和近年来这一领域的研究进展做一综述。
Interferons (IFNs)is glycoprotein secreted by many kinds of cells. It has multiple roles in antivirus, anti-tumour and immunity regulation. More and more evidences have proved that IFNs may play important roles not only in implantation and maintenance of pregnancy, but also during early embryo development. The mechanism of IFNs and progress of its role in early embryonic development were summarized.
出处
《中国生物工程杂志》
CAS
CSCD
北大核心
2006年第8期123-126,共4页
China Biotechnology
基金
国家"973"计划资助项目(2000016107)
关键词
干扰素
早期胚胎发育
哺乳动物
Interferon Early embryonic development Mammalian