期刊文献+

干扰素在哺乳动物早期胚胎发育中的作用 被引量:1

Research Progress in the Roles of Interferons During Mammalian Early Embryonic Development
下载PDF
导出
摘要 干扰素是由多种细胞产生的可溶性糖蛋白,具有广泛的抗病毒、抗肿瘤和免疫调节作用。但是越来越多的实验结果表明干扰素在哺乳动物胚胎植入子宫、怀孕的维持以及早期胚胎发育中发挥着重要作用。结合本实验室的研究工作对干扰素的作用机制和近年来这一领域的研究进展做一综述。 Interferons (IFNs)is glycoprotein secreted by many kinds of cells. It has multiple roles in antivirus, anti-tumour and immunity regulation. More and more evidences have proved that IFNs may play important roles not only in implantation and maintenance of pregnancy, but also during early embryo development. The mechanism of IFNs and progress of its role in early embryonic development were summarized.
出处 《中国生物工程杂志》 CAS CSCD 北大核心 2006年第8期123-126,共4页 China Biotechnology
基金 国家"973"计划资助项目(2000016107)
关键词 干扰素 早期胚胎发育 哺乳动物 Interferon Early embryonic development Mammalian
  • 相关文献

参考文献19

  • 1Isaacs A,Lindermann J.Virus interference,I.The interferon.Proc R Soc Lond,1957,147:258.
  • 2Bach E A,Aguet M,Schreiber R D.The IFN gamma receptor:a paradigm for cytokine receptor signaling.Annu Rev Immunol,1997,15:563 ~591.
  • 3Stark G R,Kerr I M,Williams B R,et al.How cells respond to interferons.Annu Rev Biochem,1998,67:227 ~264.
  • 4Darnell J D,Kerr IM,Stark G R.Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins.Science,1994,264:1415 ~1421.
  • 5Der S D,Zhou A,Williams B R G,et al.Identification of genes differentially regulated by interferon a,b and c using oligonucleotide arrays.Proceedings of the National Academy of Sciences,1998,95:15623 ~ 15628.
  • 6Takaoka A,Mitani Y,Suemori H,et al.Cross talk between interferon-γ and-α/β signaling components in caveolar membrane domains.Science,2000,288:2357~2360.
  • 7Ushizawa K,Herath C B,Kaneyama K,et al.cDNA microarray analysis of bovine embryo gene expression profiles during the pre-implantation period.Reprod Biol Endocrinol,2004,2:77 ~ 93.
  • 8Takahashi M,Takahashi H,Hamano S,et al.Possible role of interferon-τ on in vitro development of bovine embryos.J Rep Dev,2003,49:297~ 305.
  • 9Lefevre F,Boulay VA.A novel and atypical type one interferon gene expressed by trophoblast during early pregnancy.J Biol Chem,1993,268:19760 ~ 19768.
  • 10La Bonnardière C,Martinat-Botte F,Terqui M,et al.Production of two species of interferon by Large White and Meishan pig conceptuses during the peri-attachment period.J Reprod Fertil,1991,91:469 ~478.

同被引文献17

  • 1史喜菊,汪明,夏春.牛干扰素研究进展[J].中国兽医杂志,2005,41(6):41-43. 被引量:10
  • 2侯云德.干扰素研究的意义[J].中华实验和临床病毒学杂志,2005,19(3):205-206. 被引量:6
  • 3Domeika K..Porcine immunology regulatory cytokines with special reference to their induction by CpG containing DNA[D].Uppsala:Swedish University of Agricultural Sciences,2003
  • 4Martal JL.,Chene NM.,Hutnh LP..IFNtau,a novel subtype IFN1,structural characteristics,nonubiquitous expression,structure function relationships[J].A pregnancy hormonal embryonic signal,2006,12(22):12-23
  • 5HirokiAioa.Identification of interferon-α In the materal fetal interface in shi ba goats[J].Journal of Reproduction and Devlopment,1999,45:205-257
  • 6ChaoWuxiao.Down-regulation of oxytocin-induced cyclooxy-genase-2 prostagland in Fsynthase expression by interferon-τ in bovine endometrial cells[J].Biology of Reproduction,1999,60:656-663
  • 7Kohen P.,Castro A.,Caballero PC.,et al.Interleukine-1beta is a modulator of human luteal Cell steroidogenesis:localization of the IL typeI system in the corpus luteum[J].Clin Endocrinol Metab,1999,84:4239-4245
  • 8Karstrom EL.,Runesson E.,Bostrom EK.,et al.Selective presence of the chemokine growth regulated on cogene alpha in the human follicle and secretion from cultured granulosalutein cells at ovulation[J].Mol Hum Reprod,1998,4(11):1077-1083
  • 9Machelon V.,Nome F.,Machelon V.,et al.Regulated on activation normal T expressed and secreted chemokine is induced by tumornecrosis factoral phaing ranulosa cells from human preovulatory follicle[J].Clin Endocrinol Metab,2000,85(1):417-424
  • 10Townson DH.,Warren JS.,Flory GM..Expression of monocytechemo attractant protein in the corpus luteum of the rat[J].BiolReprod,1996,54(2):513-520

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部