5年间检出鲍曼不动杆菌及耐药性变迁的分析

The variations of drug resistance of Acinetobacter baumanii detected in the last five years.

目的 了解深圳市第二人民医院2001～2005年检出鲍曼不动杆菌的标本来源、分布及耐药变迁趋势，为有效防控制感染、指导临床合理用药提供依据。方法 回顾性调查和统计该院2001年1月～2005年12月临床送栓标本中鲍曼不动杆菌栓出情况并分析。结果 鲍曼不动杆菌栓出由2001年全年12株上升至2005年全年63株。5年中发现一株全耐株；高耐株、泛耐株共占15．6%。对鲍曼不动杆菌最为敏感的药物是亚胺培南。临床分离的鲍曼不动杆菌主要来源于痰标本占60．1％，其主要来自呼吸科。结论 鲍曼不动杆菌的感染率和耐药率正在不断上升．应重视防治。

Objective To understand the variations of tendency of drug - resistance, the origin and the distributing of Acinetobacter baumannii and provide basis for selection of chnical drugs. Methods The data concerning Acinetobacter baumannii infection in our hospital in 2001 - 2005 were retrospectively and statistically analyzed. Results The total strains of Acinetobacter baumannii isolated from this hospital was increased from 12 strains in 2001 to 63 strains in 2005 , and a panresistant strain was detected in the last five years. High drug- resistance and pan- resistant strains were accounted for 15.6%. Acinetobacter baumannii was most sensitive to imipenem. 60% of Acinetobacter baumannii were isolated from sputum specimens. Conclusion The infection rate of Acinetobacter baumannii is increasing and measures be adopted for control Acinetobacter baumannii infection in hospital.