稳心颗粒治疗心律失常112例临床观察

The Effects of Wenxinkeli on 112 Patients with Arrhythmias

目的:观察稳心颗粒治疗心律失常的临床效果及安全性。方法:对112例有(或无)心悸等主观不适,并有心电图及动态心电图证实有心律失常,如频发房性期前收缩、短阵室上性心动过速或心房纤颤、室性期前收缩、或伴有短阵室性心动过速患者,采用单盲法观察。在前一周内未用过其它抗心律失常药物,开始服用稳心颗粒9 g(1袋),3次/d,连续治疗4周,记录患者的症状和不良发应,并有心电图及动态心电图作前后对照。结果:其治疗心律失常的有效率分别为:房早45.80%,室早49.27%,症状缓解86.50%,且无明显不良反应。结论:稳心颗粒对频发房早、室早的总有效率与口服普罗帕酮、胺碘酮等抗心律失常药的有效率相接近;而对窦性心率几无影响,且在减少早搏的同时能减轻症状,这优于普罗帕酮、胺碘酮等。

Objective：To observe the clinical effect and safety of Wenxinkeli on the patients with arrhythmia. Methods： 112 patients who have（or no）palpitation with electrocardiogram and holter proving arrhythmias including superaventricular arrhythmias, premature ventricular beats, ventricular tachycardia were given Wenxinkeli 9 g rid for 4 weeks without other anti-arrhythmias medicine in a week ahead recording the symptoms and the side reaction with electrocardiogram and holter. Results ： Effective rate on arrhythmiasis ： 45.80 % for atrial premature beats, 49.27 % for premature ventricular beats,86.50 % for symptom lysisand and no obvious side reaction was found. Conclusion：Wenxinkeli is similar in efficiency to propafenone and Amiodarone and other same anti-arrhythmia medicin. However, it is no effect on sinus heart rate and relieve the symptoms as relieving the premature beats which is better than propafenone and Amiodarone.