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U2afbp-rs基因研究进展

Advance in the Study of U2afbp-rs Gene
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摘要 U2afbp-rs基因是一个印记基因,它在附植前胚胎中就表现出强烈的印记作用。因此,U2afbp-rs基因是研究体细胞核移植过程中卵细胞质对供体核DNA甲基化和印记基因表达调控的良好模型。本文对国内外有关U2afbp-rs基因的研究进展,特别是对U2afbp-rs基因的定位、结构、印记机制以及其在胚胎中的表达特征进行了综述。 U2afop-rs, an imprinting gene, has shown sharp imprinting in embryo during preimplantation development. Therefore, U2afop-rs gene is an ideal model for the re＇search on how oocyte cytoplasm regulates the DNA methylation of the donor nuclear and the expression of imprinting gene during the process of somatic nuclear transplantation. The orientation, structure, imprinting mechanism and the expression of U2afbp-rs gene are discussed in this review.
作者 李少华 刘红林
机构地区 南京农业大学动物科技学院
出处 《国际遗传学杂志》 CAS 2006年第3期226-230,共5页 International Journal of Genetics
基金 国家自然科学基金(No.30471244)
关键词 U2afbp-rs基因 印记 表达特征 U2afop-rs gene Imprinting Expressive characteristics
分类号 Q343 [生物学—遗传学]
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参考文献31

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二级参考文献31

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共引文献14

国际遗传学杂志
2006年 第3期

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