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MSX1基因与非综合征性唇腭裂

MSX1 Gene and Nonsyndromic Cleft of Lip and Palate
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摘要 非综合征性唇腭裂是最常见的先天性畸形之一,是一种多基因遗传病。大量的遗传和流行病学手段被用于该疾病候选基因的病因学研究。现就MSX1基因与非综合征性唇腭裂之间的关系进行了综述,为该疾病的病因学研究提供了一个重要的线索。 Nonsyndromic cleft lip and/or palate（NSCLP） is one of several complex human birth defect traits that are thought to be caused by a combination of genes and environmental interactions. A variety of genetic and epidemiologic approaches have been used to identify etiology with candidate genes. This review is intended to summarize the studies of the polymorphisms of MSX1 gene and its correvation with NSCLP, which offers an important clue to etiology study of this disease.
作者 吴平安 李运良
机构地区 中南大学湘雅二医院口腔科
出处 《国际遗传学杂志》 CAS 2006年第4期299-302,共4页 International Journal of Genetics
关键词 MSX1 非综合征性唇腭裂 基因 MSX1 Nonsyndromic cleft lip and/or palate Gene
分类号 R782 [医药卫生—口腔医学]
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参考文献22

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国际遗传学杂志
2006年 第4期

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