3-乙酰基-2-芳基-5-(2-碘苯基)-1,3,4-噁二唑啉化合物的合成与表征

Synthesis and characterization of 3-acetyl-2-aryl5-(2-iodophenyl)-1,3,4-oxadiazolines

2-碘苯甲酰肼与八种芳醛反应得到相应的酰腙(1 a^1h),后与乙酸酐脱水环化合成3-乙酰基-2-芳基-5-(2-碘苯基)-1,3,4-噁二唑啉化合物(2 a^2h),通过元素分析、IR、1H NMR和MS对化合物2 a^2h的结构进行了表征。

The reaction of 2-iodobenzoyl hydrazine with arylaldehydes gave the corresponding hydrazones （ 1a～1h）. Then 1a～1 h respectively cyclodehydrated with acetic anhydride to afford 3-acetyl-2-aryl-5- （2-iodophenyl） -1,3,4-oxadiazolines （2a～2h）. The structures of 2a ～2h were characterized by elementary analysis,IR,lH NMR and MS.