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水通道蛋白-1在培养的牛角膜内皮细胞中的表达研究 被引量：1

Research of the expression of aquaporins-1 in corneal endothelial
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摘要 目的研究水通道蛋白-1在培养的牛角膜内皮细胞中的表达情况及意义。方法用免疫组织化学方法,检测水通道蛋白-1在培养的牛角膜内皮细胞中的表达。结果培养的牛角膜内皮细胞中有水通道蛋白-1的表达,且主要位于细胞膜上。结论牛角膜内皮细胞中的水通道蛋白-1在角膜内皮液体转运中起着重要作用,其表达改变可能导致角膜水肿和功能改变。 Objective To investigate the expression of aquaporins-1 （ AQP-1 ） in cultured bovine corneal endothelial cells （CBCEC） . Methods Immunohistoehemisty was used to detecting AQP-1 expression in CBCEC. Results The presence of AQP-1 antibody was major located in CBCEC membrane. Conclusion AQP-1 in CBCEC play an important role in corneal endothelial cell＇ s fluid transport, its expression change may cause corneal edema and function disorder.
作者 张红旭 张明昌
机构地区 华中科技大学同济医学院附属协和医院眼科
出处 《临床眼科杂志》 2006年第5期466-467,共2页 Journal of Clinical Ophthalmology
关键词 角膜内皮 水通道蛋白-1 牛 Cornea Endothelium Aquaporin-1 Bovine
分类号 R77 [医药卫生—眼科]
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参考文献7

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同被引文献15

  • 1关兵,董震.水通道蛋白与肿瘤[J].中国肿瘤临床,2005,32(13):777-780. 被引量：7
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临床眼科杂志
2006年 第5期

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