黄连素治疗老年2型糖尿病神经病变的临床观察

Clinical Observation on Senile Diabetes II Nerve Lesion Treated with Berberine

目的观察黄连素治疗老年糖尿病周围神经病变的疗效及安全性。方法54例老年糖尿病神经病变患者入选本研究,并随机进入黄连素组(27例)和弥可保组(27例)。黄连素每天3次,每次4片,弥可保每天1次肌肉注射,每次1支,共12周。结果12周后,弥可保组对疼痛、麻木的改善显效率明显高于黄连素组。结论弥可保对老年2型糖尿病神经损害的症状改善有较好疗效,但对神经传导速度两组无明显差异。

[Objective] Observe the effect and safety of berberine in treating senile diabetes Ⅱ peripheral nerve lesion. [Method] Select 54 patients of senile diabetes Ⅱ peripheral nerve lesion into the study, and divide them randomly into berberine group（27 cases） and Mikebao group（27）. The berberine was applied 3 times each day, 4 tablets one time; Mikebao was administered intramuscular injection one time each day, 1 piece one time, both for 12 weeks. [Result] After 12 weeks, the relieving of pain and numbness was much better in the Mikehao group than berberine group. [Conclusion] Mikebao has better effect in relieving symptoms of senile diabetes Ⅱ peripheral nerve lesion, but there＇s no marked difference between 2 groups on nerve conduction speed.