川崎病致多脏器损害68例临床分析

Clinical Analysis on Multi-organ Injury Caused by Kawasaki Disease

目的总结川崎病的临床表现及多脏器损害情况,提高诊治水平。方法对我院1990年8月至2005年8月收治的68例川崎病进行临床分析。结果68例患儿中5岁以内占76·5%,男女之比为1·43∶1,可致多脏器损害,以心血管系统、呼吸系统、血液系统为主,最严重为冠状动脉病变,占33例(48·5%)。以治疗原发病为主,各系统症状随着原发病的好转而恢复。结论川崎病是儿童后天性心脏病的主要病因,了解川崎病的多系统损害,有利于早期诊断,早期用药,减少多脏器损害。

[Objective] Summarize the clinical symptoms and multi-organ injury, improve diagnosis and treatment. [Method] Make clinical analysis on 68 cases of Kawasaki disease selected from Aug. 1990 to Aug. 2005 in our hospital. [Result] Among them, patients over 5 years old occupied 76.5 %, the ratio of male and female was 1.43 ： 1, it could cause multi-organ injury, mainly myocardial-vascular system, respiratory system and blood system, the most severe was lesion of coronary artery, occupying 33 cases （48.5%）. Its treatment centered on primary disease, and the symptoms in all systems were relieved with the primary disease. [Conclusion] Kawasaki disease is the main cause of children＇s acquired heart disease; to understand multi-organ injury is helpful to early diagnosis, medicine application and reduce multi-organ injury.