摘要
目的制备黄柏治糜栓并制订其质量控制标准。方法以黄柏、蒲公英、苦参、血竭、紫花地丁、紫草6味中药为主药,半合成脂肪酸(38型)为栓剂基质制成栓剂,采用高效液相色谱法(HPLC法)测定苦参中氧化苦参碱的含量,同时用薄层色谱法对制剂中的黄柏、蒲公英、紫花地丁进行鉴别。结果HPLC法的平均回收率为99.47%,RSD为1.24%。结论该制剂制备方法简便,质量稳定,检测方法可靠。
Objective To study the preparation of Huangbaizhimi suppository and to establish its quality control standard, Methods The content of oxymatrine in Radix Sophorae flavescentis was determined by HPLC, and Cortex Phellodendri, Herba Taraxaci, Herba Violae in products were indentified by TLC. Results The average recovery rate of three concentrations （high,middle,low） was 99.47% with RSD 1.24%. Conclusion The product preparation method is simple,the quality is stable,the examination method is credibility.
出处
《中国药业》
CAS
2006年第16期32-34,共3页
China Pharmaceuticals
关键词
黄柏治糜栓
苦参
制备
质量控制
Huangbaizhimi suppository
Radix Sophorae flavescentis
preparation
quality control
