期刊文献+

Synthesis and Crystal Structure of N′-(4-fluorobenzylidene)-2-(1H-1,2,4-triazole-1-yl)acetohydrazide

Synthesis and Crystal Structure of N′-(4-fluorobenzylidene)-2-(1H-1,2,4-triazole-1-yl)acetohydrazide
下载PDF
导出
摘要 N′-(4-fluorobenzylidene)-2-( 1H-1,2,4-triasole-1-yl) acetohydrazide was synthesized by the reaction of 4-flu- orobenzaldehyde with 2-( 1H-1,2,4-triazole-1-yl) acetohydrazide. The structure was confirmed via elemental analysis, MS, ^1H NMR, IR, and X-ray diffraction. It crystallized in a monoclinic system with space group P2 ( 1 ), α = 0.4905(1) nm, b =0. 8160(2) nm, c = 1.4105(3) nm, β =93. 33(3)°, Z=2, V=0.5636(2) nm^3, Do =1.457 Mg/m^3,μ =0. 112 mm^-1 , F(000) =256, and final R1 =0. 0685. Several intermolecular hydrogen-bond interactions existed in the crystal structure, facilitating the stabilization of the compound. N′-(4-fluorobenzylidene)-2-( 1H-1,2,4-triasole-1-yl) acetohydrazide was synthesized by the reaction of 4-flu- orobenzaldehyde with 2-( 1H-1,2,4-triazole-1-yl) acetohydrazide. The structure was confirmed via elemental analysis, MS, ^1H NMR, IR, and X-ray diffraction. It crystallized in a monoclinic system with space group P2 ( 1 ), α = 0.4905(1) nm, b =0. 8160(2) nm, c = 1.4105(3) nm, β =93. 33(3)°, Z=2, V=0.5636(2) nm^3, Do =1.457 Mg/m^3,μ =0. 112 mm^-1 , F(000) =256, and final R1 =0. 0685. Several intermolecular hydrogen-bond interactions existed in the crystal structure, facilitating the stabilization of the compound.
出处 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2006年第5期571-573,共3页 高等学校化学研究(英文版)
关键词 1H-1 2 4-TRIAZOLE Acetohydrazide Crystal structure Biological activity 1H-1,2,4-Triazole Acetohydrazide Crystal structure Biological activity
  • 相关文献

参考文献15

  • 1Xu L. Z., Jian F. F., Shi J. G., et al. , Chinese J. Chem.,2004, 22,698
  • 2Wlimesova V. , Otocenasck M. , Waissor K. L. , Eur.J. Med.Chem, 1996, 31, 389
  • 3Das A. , Trousdale M. D. , Ren E. J. , Antiviral. Res. , 1999,44,201
  • 4Shi Y. N., Fang J. X., Xu L. Z., Chem. J. Chinese Universities, 1992, 13(8), 1084
  • 5Xu L. Z. , Jiao K. , Zhang S. S. , et al, Bull. Korean Chem.Soc., 2002, 23(12), 1699
  • 6Anderson N. H. , Proceeding of the 5th International Congress of Pesticide Chemistry(IUPAC), Kyoto, 1982, 345
  • 7Dobosz M. , Sikorska M. , Acta Pol. Pharm. , 1994, 51(4/5),369
  • 8Sheldrick G. M. , SHELXTL V5.1, Software Reference Manual,Brucker AXS, Inc, Madiaion, 1997
  • 9Wilson A. J. International Table for X-ray Crystallography.,Vol. C, Kluwer Academic Publisher, Dordrecht, 1992, Tables 6. 1.1.4(p500) and 4.2.6.8(p219)
  • 10Ji B. M., Du C. X., Zhu Y., et al., Chin. J. Struct. Chem. , 2002, 21,252

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部