视网膜下液体对人视网膜神经胶质细胞生长的刺激作用与PVR关系

nal Fluid on Stimulation of Human Retinal Glial Cells and the Relationship to PVR

研究了２８例孔源性视网膜脱离患者视网膜下液（ＳｕｂｒｅｔｉｎａｌＦｌｕｉｄＳＲＦ）对人视网膜神经胶质细胞（ＲｅｔｉｎａｌＧｌｉａｌＲＧ）生长的刺激作用。结果表明：所有标本通常具有刺激ＲＧ细胞增殖能力，但存在较大范围的活动性，增殖率范围在基线上３６．４～１８１．８％，ＳＲＦ促ＲＧ细胞增殖能力与ＰＶＲ程度呈平行关系，ＰＶＲ在Ｃ级以上，促ＲＧ细胞增殖活力显著性加强（Ｐ＜０．０１）。

he stimulating effect of subretinal fluids(SRF) from 28 patients with rhegmatogenous retinal detachment on the growth of retinal glial(RG) cells were investigated.The results demonstrated that all samples showed a stimulating effect to RG cells in a variable degree.The range of proliferation (stimulating activity) was from 36.4～181.8% above the baseline.The ability of SRF to stimulate proliferation of RG cells was paralled with the degree of PVR.When PVR was above C grade,the ability of SRF to stimulate proliferation of RG cells was increased (P<0.01).