^(18)FDG-PET在直肠、结肠癌诊断中的价值初探

The Primary Value of ^(18)FDG-PET in Diagnosis and Staging of Colorectal Carinoma

对24例经肠镜检查初步诊断为直肠、结肠癌的患者进行18FDG-PET显像研究,评价18FDG-PET对大肠癌诊断、分期及治疗计划的价值。结果表明,24例病理证实为大肠癌的患者,23例局部18FDG摄取增高(SUVmax=7.09±3.26,2.98~12.2)1。8FDG-PET对于肿瘤原发病灶诊断准确率为95%(23/24),假阴性1例,8例远处转移全部检出;对于单纯局部(主要为第1站)淋巴结转移灵敏度为50%(8/16),特异性为100%;改变了33%(8/24)患者的治疗方案。因此,18FDG-PET对大肠癌原发病灶诊断灵敏度高,假阴性率低,但鉴别原发病灶早期局部侵犯程度作用有限;18FDG-PET对于淋巴结、肝、骨骼等远处转移探测效率高;18FDG-PET对大肠癌的分期和治疗计划制定有一定的价值。

In order to evaluate the value of ^18SFDG-PET in the diagnosis and staging of colorectal carcinoma, 24 patients with potentially colorectal carcinoma are made ^18FDG-PET examination. The primary results show that the primary tumour is visualized in 95% with PET（SUVmax=7.09±3.26,2. 98-12.2）. Distant metastases are found in eight patients entirely. For local-regional lymph nodes,the sensitivity is 50%, the specificity is 100%. 33% of patients are facilitated in the treatment planning. ^18FDG-PETcandetect primarycolorectal carcinomar and metastasis of lymph node ,liver, bone sensitively. ^18FDG-PET is of little use for determinant of stage. ^18FDG-PET is useful in the staging and treatment of colorectal of carcinoma.