摘要
1991年10月至1992年12月,作者在前期研究的基础上,采用食管癌放疗加光动力学疗法60例随机分组研究。对照组:30例,单纯体外放疗DT60~66Gy/6~7周;实验组:30例,体外放疗同对照组,只是当Dr40Gy/4周时加用PDT。结果显示:对照组和实验组近期疗效(Ⅰ+Ⅱ级X线片)、1、3年生存率对照组分别为:66.7%(20/30)、46.7%(14/30)、16.6%(5/30);实验组分别为:83.3%(25/30)、76.7%(23/30)、30.0%(9/30)。实验组高于对照组,其中1年生存率实验组明显高于对照组,(P<0.05)。作者认为放疗加光动力学疗法优于单纯放疗,是治疗中晚期食管癌的一种有效方法。
rom October l99l to December l992,on the basis of the firststage(prophase)researchwork,radiotherapy combined with photodynamics were adopted for 60 cases of esophagealcancer,which were randomly divided into two groups the control group(CG)and the treat-ment group(TG),each group comprising 30 patients,For the CG,the approach of DT6066Gy for 6~7 weeks for extracorporeal radiation was adopted.Extracorporeal radiation giv-en to the TG was the same as that offered to the CG,except for the addition of PDT whenthe DT 40Gy was given for 4 weeks,The short-term curative effect,one-year and three-yearsurvival rates seen in the CG were 66.7%(20/30),46.7%(14/30)and l6.6%(5/30)respec-tively,Such rates happening in the TG were 83.3%(25/30),76.7%(23/30)and 30,3%(9/30) respectively.What was shown in the TG was apparently higher than that seen in the CG(P<0.05).The author holds that radiotherapy combined with photodynamic therapy wassuperior to using radiotherapy alone,representing an efficient way in the treatment of advanced carcinoma of the esophagus.
出处
《上海医学》
CAS
CSCD
北大核心
1996年第10期573-575,共3页
Shanghai Medical Journal
关键词
食管肿瘤
光动力学疗法
Esophageal cancer
Radiotherapy
Photodynamic therapy