新生儿缺氧缺血性脑病合并心肌损害50例临床分析

Clinical analysis of 50 cases of newborns with hypoxic-ischemic encephalopathy complicating cardiac damage

目的:探讨新生儿缺氧缺血性脑病(HIE)合并心肌损害临床特征,指导进一步的治疗。方法:对72例HIE患儿进行心脏功能检测及临床观察与评价。结果:72例HIE患儿中合并心肌酶谱异常50例(69.4%),而且伴有心音低钝、心率改变。结论:HIE患儿临床观察中,若出现心音或心率的异常,应检测心肌酶谱尤其是CK-MB,如果心肌酶谱异常,应高度警惕合并心肌损害的可能。

Objective： To investigate the condition of newborns with hypoxic-ischemic encephalopathy （HIE） complicating cardiac damage. Methods： 72 patients with HIE were determined cardial zymogram and ECG, and the changes of cardiechema and heart rate were observed to evaluate the degree of cardiac damage. Results： There were 50 patients complicating cardiac damage in 72 newborn with HIE, 45 patients had ECG abnormality and all of them had abnormality in cardial zymogram. Conclusions： These results indicated that cardial zymogram and ECG are important in early diagnosis of newborns with HIE complicating cardiac damage. At the same time, the changes of cardiechema and heart rate are important clinical signs at early period.