瑞芬太尼在脊柱手术中对患者血压及心率的影响

Effects of remifentanil on BP and HR during spinal column operation

[背景]观察瑞芬太尼在脊柱手术期间对患者血压及心率的影响．[病例报告]选择40例择期手术患者，随机分为对照组和观察组，每组各为20例．麻醉维持期给两组患者静脉注入异丙酚6mg／（kg·h），仙林每30min 4mg，吸入20～30mL儿安氟醚，观察组患者追加给予静脉注入瑞芬太尼0．05～0．10μg／（kg·min）．观察记录手术前及手术开始后5，15，30，45min时患者收缩压及心率．与麻醉前比较，对照组患者麻醉期间收缩压及心率均明显升高，而观察组患者均显著下降，两者间差异有统计学意义．[讨论]瑞芬太尼可有效地降低手术期间患者的血压及心率，减少手术视野出血，保持血液动力学指标稳定．

BACKGROUND To study the effects of remifentanil on BP and HR during spinal column operation. CASE REPORTS 40 patients were randomly divided into two groups, control and observation with 20 cases each, both of them were administrated with propofol 6 mg/（kg＇h）, vecuronium bromide per 30 min 4 mg, enflurane 20- 30 mL/L during anesthesia. And in observation group remifentail was injected intravenously 0.05--0.10 μg/（kg·min）. To record the BP and HR 15, 30, 45, 60 min in both groups. BP,HR were higher during anesthesia than before anesthesia significantly in control group; BP,HR were lower during anesthesia than before anesthesia significantly in observation group. DISCUSSION Remifentail take from the BP,HR effectively during operation, reduce the blooding, ensure the operative field clean and maintain the hemodynamics tranquilization, so as to the operation go with a swing.