摘要
目的:探讨糖尿病肾病患者的血清sICAM-1水平在糖尿病肾病发生、发展过程中的作用及临床意义。方法:应用酶联免疫吸附法(ELISA)检测了60例2型糖尿病患者血清sICAM-1水平,并与30例健康人作对照,且与空腹血糖、尿微量白蛋白进行相关分析。结果:2型糖尿病患者血清sICAM-1水平高于对照组,糖尿病肾病组高于糖尿病无肾病组,糖尿病无肾病组高于正常对照组,差异有显著意义(P<0.01),且与空腹血糖、尿微量白蛋白等密切相关。结论:血清sICAM-1参与了糖尿病肾病的病变过程,可作为糖尿病肾病病情变化的监测指标。
Objective： To study the change and significance of soluble intercellular adhesion molvcule-1 （sICAM -1） level in patients with type 2 diabetic nephropathy. Methods： Tbe concentration of slCAM-1 in 60 cases of type 2 diabetes mellitus and 30 normal controls were detected with ELISA and combined with the levels of fasting blood glucose （FBG）, urine micro album in （MA 1b ） for correlation analysis, Results： sICAM -1 level in patients with diabetic nephropathy was higher than those in normal controls （P 〈0.01） and closely related to the levels of FBG,MA lb （P 〈0.01）. Conclusion： Higher sICAM -1 level maybe contribute to the occurrence and development of diabetic nephropathy.
出处
《实用中西医结合临床》
2006年第5期12-13,共2页
Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
