超声背向散射积分对均匀性脂肪肝定量诊断与病理对照研究

Effect of Ultrosonic Integrated Backscatter on Quantitive Diagnosis of Homogeneous Fatty Liver and Comparision With Pathologic Results

目的:应用声学密度定量技术对胆结石手术患者中均匀性脂肪肝肝实质近场进行声学定量分析,并与病理结果对照,探讨该技术对均匀性脂肪肝定量诊断的临床应用价值。方法:用配置AD(声学密度)装置和声学定量分析系统的HP—5500型超声诊断仪对预行胆结石手术的不同程度的均匀性脂肪肝患者及对照组正常肝进行近场深度的背向散射积分(IBS)测定,取其平均值并与病理结果对照研究,分组进行统计学分析。结果:本课题对66例病人术前图像采集进行了IBS测定,术中取活检,术后病理证实,病理确诊的63例轻、中、重度均匀性脂肪肝及正常肝近场IBS标化值有显著性差异,P<0.05,各组IBS标化值以均数±标准差(-x±SD)表示,为临床提供参考。结论:声学密度定量技术用于均匀性脂肪肝的诊断准确、客观,能为临床提供一项数字定量化、标准化的新指标。

Objective： To explore the clinical value of acquisition densitometry （A D） through quantitive analysis of AD in near field of homogeneous fatty liver in gallstone patients and comparision with pathnologic resuits. Methods：Using HP SONOS 5500 ultrasonic apparatus,ultrasonic integrated backscatter （IBS） of liver was quantitively analysed in near field of various grades of homogen eous fatty liver in preoperative group and in normal liver in control group. The average IBS was compared with pathologic results. Results： In 66 patients with homogeneous fatty liver, IBS was detected with preoperative image collection, biopsy was getted during operation and pathologic results were confirmed. According to pathologic results, 66 patients were divided into four groups： control group, mild fatty liver group, moderate fatty liver group and severe fatty liver group. There was significant difference in IBS values among groups （P 〈 0.05）. Conclusion：AD is accurate and objective in diagnosis of homogeneous fatty liver. It provides a quantitive and standard index for clinical diagnosis.