颈动脉粥样硬化与脑梗死的相关分析

Study of carotid artery plaque and relative factors in cerebral infarction patients

目的探讨急性脑梗死患者颈动脉粥样硬化斑块的发生与相关因素。方法应用美国ATL-5000彩色多普勒超声诊断仪,分别对急性脑梗死组(120例)和对照组(45例)行颈动脉超声检测,观察颈动脉粥样硬化斑块的发生与血糖、血脂、血浆纤维蛋白原的关系。结果急性脑梗死患者颈动脉粥样硬化斑块的发生率为82.5%,对照组为33.3%,两者比较差异有统计学意义(P<0.01);急性脑梗死患者颈动脉粥样硬化斑块好发于分叉处;梗死侧颈动脉粥样硬化斑块发生率高于非梗死侧;两者比较差异有统计学意义(P<0.01);年龄、高血压、糖尿病、高胆固醇、血浆纤维蛋白原和低密度脂蛋白升高是脑梗死患者颈动脉粥样硬化斑块形成的危险因素。结论颈动脉粥样硬化与脑梗死有密切相关性。超声检查能早期发现颈动脉粥样硬化,对有效预防脑梗死的发生有重要意义。急性脑梗死患者普遍有颈动脉粥样斑块的形成,是急性脑梗死发病的重要因素之一。

Objective To explore the prevalence of carotid ship between carotid artery plaque and relative factors. Methods artery plaque in acute cerebral infarction patients and the relation Carotid artery was evaluated by HDI-5000 color Doppler ultra sound in cerebral infarction group （n= 120）and control group（n=45）. Blood glucose , blood lipid and blood fibrinogen were examined in two groups and their relationship with carotid artery plaque were analysed. Results The prevalence of cartid artery plaque in aeute cerebral infarction group and control group were 82.5 N and 33.3 % respectively（P〈0.01）. In acute cerebral infarction group, the plaque was located in the bifurcation of the carotid artery. The plaque occurrence rate was higher in cerebral artery than that in non - cerebral arteries （P〈0.01）. Age ,hypertension, diabetes mellitus, high serum cholesterol , high fibrinogen and high low density lipoprotein-cholesterol were risk factors for carotid artery plaque in acute cerebral infarction patients. Conclusion There is a close relationship between carotid artery plaque and acute cerebral infarction. Color Doppler ultrasound is an important method for the diagnosis and treatment of cerebral infarction.