依达拉奉治疗急性脑梗死的疗效观察

Clinical efficacy of edaravone on acute cerebral infarction

目的观察依达拉奉对急性脑梗死的治疗效果。方法将60例脑梗死患者随机分为治疗组和对照组。治疗组在常规治疗的基础上,给予依达拉奉30mg+5%葡萄糖或生理盐水100ml静滴,30min内滴完,2次/d,共10d。治疗组和对照组于治疗前及治疗后第10d分别进行神经功能缺损评分及疗效评定。结果治疗10d后,治疗组神经功能缺损为(9.7±6.4)分,明显低于对照组(14.5±7.2)分(P<0.05);治疗组显效率和有效率分别为48.4%和86.7%,显著高于对照组的20.2%和61.9%(P<0.05)。结论依达拉奉可促进急性脑梗死患者的神经功能康复。

Objective To evaluate the efficacy of edaravone on the treament of acute cerebral infraction . Methods 60 cases were divided into treated group and control group randomly. The patients in treated gronp were given edaravone 30mg added to 5 glucose or NS 100ml,by ivgtt, twice a day, the whole duration was 10 days. Neurological function deficit scores were utilized for assessment before given treatment. On the 10th day after treatment, the patient was assessed again and the efficacy was recorded. Resuits After 10 days treatment ,the neurological function deficit scores of treated group were 9.7± 6.4,whereas those of the control group were 14.5±7.2 . There was significant difference between the two groups （P〈0. 05）. Conclusion Edaravone can accelerate the recovery of neural function after acute cerebral infarction.