摘要
通过对重庆市部分养殖场分离到的120株致病性大肠杆菌进行了耐药谱的调查,并利用加有100μmol/l的黄连、丹参提取液的培养基进行感触培养,观察培养前后大肠杆菌对氟喹诺酮类药物耐药谱的变化。试验结果显示,经两种不同中药提取液感触培养后,8耐以上的菌株从72.5%分别下降到61.7%和54.2%。表明中药可部分逆转致病性大肠杆菌对氟喹诺酮类药物的耐药性。
120 strains of E. coli, isolated from breeding farms in Chongqing, were cultured in the medium to which were added 100 μmol/l herbal medicine liquid extracted from Rheum officinale Baill. and Salvia miltiorrhiza Bunge to investigate the baeteria＇s resistance to fluoroquinolones （FQs）. The results showed the number of strains resistant to 8 - 11 kinds of FQs decreased from 72. 5% to 61.7% and 54.2% after cultured in two herbal medicine extracted liquid. It is concluded that the herbal medicine can partly eliminate the resistance of E. coli to fluoroquinolones.
出处
《中兽医医药杂志》
2006年第5期7-9,共3页
Journal of Traditional Chinese Veterinary Medicine
基金
重庆市教委项目
项目编号:290501
关键词
黄连
丹参
大肠杆菌
氟喹诺酮类抗菌药
Rheum officinale Baill.
Salvia miltiorrhiza Bunge
E. coli
fluoroquinolones
drug resistance
