SPECT评价体外反搏治疗缺血性脑血管病

Assessment of the efficacy of external counter pulsation treatment in ischemic cerebral vascular diseases by brain SPECT imaging

２２例经临床及实验室检查诊断为缺血性脑血管病患者在体外反搏治疗前后用９９ｍＴｃ－双胱乙酯（ＥＣＤ）行ＳＰＥＣＴ局部脑血流（ｒＣＢＦ）断层显像。治疗前显示ｒＣＢＦ缺血改变５４处，治疗后明显改善的２０处，占３７．０％；部分改善１９处，占３５．２％；无效１５处，占２７．８％；总有效率为７２．２％。结果表明，ＳＰＥＣＴ可用于缺血性脑血管病的早期诊断，还可用以评价缺血性脑血管病的疗效。

Twenty-two cases of ischemic cerebral vascular disease, diagnosed by clinical and experimental methods, were examined with 99mTc-ECD SPECT regional cerebral blood flow (rCBF) tomography adaging before and after treatment with exterenal counter pulsation (ECP). Before the treatment, there were 54 segments deficient in rCBF, while after the treatment 20 segments fully improved (37.5%), 19 segments podly approved (35.2%) and 15 segments not changed (27.8%).Therefore, totalefficacy reached up to 72.2%(39/54). The result suggested that SPECT is useful notonly for early diagnosis but also for the evaluation of the curative effect on ischemic cerebral vascular disease.