多时段血糖控制对糖尿病心血管病变转归的影响

ANALYSIS OF 2-YEAR FOLLOW-UP ON CARDIOVASCULAR DISEASE IN PATIENTS UNDER TEST AND CONTROL OF BLOOD GLUCOSE MORE THAN 6 TIMES IN ONE DAY

目的:探讨多时段血糖控制对糖尿病心血管病变治疗上的作用。方法:对76例确诊2型糖尿病病人进行每月多时段血糖监测及根据结果进行降糖药物调整使血糖稳定,观察2年。对照组为35例根据空腹及早餐后血糖监测调整降糖药物。所有病人定期检查血糖、血压及糖化血红蛋白(HbA1c)、心电图、心脏B超、动态心电图(Holter)等。结果:糖尿病心血管病变发生或发展情况经过秩和检验,两组间结果比较差异有统计学意义(P<0.05)。结论:多时段血糖控制可延缓2型糖尿病心血管病变的发生并对心血管病变有改善作用。

Objective：To study the therapeutic effect multi-times/day control of blood glucose on treatment of diabetic cardiovascular disease. Methods：76 instances with type-2 diabetes（as experimental group） were treated with more than 6 points of blood glucose test and controlled in one day for each month, but the other 35 cases as control group were treated with 2 points of blood glucose test and controlled in a day morning each month. All patients were observed for 2 years,and regularly examined for urinary protein, blood glucose,blood pressure and HbAlc. Result： The numbers of onset and development of diabetic cardiovascular disease in the experimental group were higher than those in the control group. Conclusion： More than 6 points of blood glucose test and control will delay the onset and development of complication as well as improve the condition of diabetic cardiovascular disease of type 2 diabetes.