幽门螺杆菌对功能性消化不良儿童胆囊排空的影响

Effect of Helicobacter Pylori Infection on Emptying of Gallbladder in Children with Functional Dyspepsia

目的了解功能性消化不良(FD)患儿胆囊排空情况及幽门螺杆菌(Hp)感染对其影响。方法FD患儿60例。其中Hp阴性组,阳性组各30例。Hp阳性组经抗Hp治疗后,Hp转阴27例,作为Hp根除组,正常对照组30例。比较各组胆囊排空情况。结果FD患儿空腹胆囊容积大,餐后胆囊排空延迟,与正常对照组比较差异有显著性(P<0.05);Hp阳性组与阴性组、根除组比较,空腹胆囊容积和餐后胆囊排空率均无明显差异(P>0.05)。结论FD儿童存在胆囊排空障碍,与Hp感染无关。

Objective To study emptying of gallbladder in children with functional dyspepsia（FD）, and to investigate correlation of their helicobacter pylori（Hp） status and gallbladder emptying rate. Methods Sixty children with FD were studied, including 30 Hp - negative and 30 Hp positive children. Thirty Hp - positive children received triple eradication therapy 1 week. After 4 weeks, the Hp tests were taken again, 27 children became Hp- negative, and the others were still positive eliminated from the study. The difference between the above groups in gallbladder volumes before breakfast and postprandial gallbladder emptying rate were compared. Results The gallbladder volumes before breakfast were bigger and the emptying rate of postprandial gallbladder of children with FD were lower than those of normal controls（ P 〈 0.05）. No difference was found in the gallbladder volumes before breakfast and postprandial gallbladder emptying rate between Hp negative group and Hp - positive group and Hp eradicated group （P 〉 0.05）. Conclusions Delayed emptying of gallbladder may cause FD in children. Hp infection isn＇t associated with the gallbladder emptying rate.