雪蛙油软胶囊抗氧化作用的研究

The Antioxidant Effects of the Snow Frog Oil Soft Capsule

背景与目的探讨雪蛙油软胶囊的抗氧化作用。材料与方法分2.5、0.5和0.1g/kg3个雪蛙油剂量实验组,给予Wistar雌性大鼠雪蛙油灌胃,同时设溶剂对照组(食用色拉油)。连续给予受试物8周后,测定血清超氧化物岐化酶(Superoxidedismutase,SOD)、谷胱甘肽过氧化物酶(Glutathioneperoxidase,GSH-Px)和肝脏的丙二醛(Malondiadehycle,MDA)。结果雪蛙油软胶囊有升高血清SOD和GSH-Px值和降低肝脏MDA值的作用。结论雪蛙油软胶囊具有明显抗氧化作用。

BACKGROUND ＆ AIM： To explore the antioxidant effects of snow frog oil capsule. MATERIAL AND METHODS： The mice were divided into four groups, study groups were given snow frog oil at a dose of 2.5, 0.5, 0.1 gAg,while distilled water was given in control group. The levels of SOD and GSH-Px in serum and the level of MDA in the liver tissue were evaluated. RESULTS： Snow frog oil capsule could increase the levels of SOD and GSH-Px in serum and decrease the level of MDA in liver tissue. CONCLUSION： Snow frog oil capsule antioxidant effects.