1Pamer EG.Immune responses to listeria monocytogenes[J].Nat Rev Immunol,2004,4(10):812
2Peng X,Hussain SF,Paterson Y.The ability of two listeria monocytogenes vaccines targeting human papillo-mavirus-16 E7 to induce an antitumor response correlates with myeloid dendritic cell function[J].J Immunol,2004,172(10):6 030
3Paterson Y,Maciag PC.Listeria-based vaccines for cancer treatment[J].Curr Opin Mol Ther,2005,7(5):454
4Avogadri F,Martinoli C,Prtrovska L,et al.Cancer immunotherapy based on killing of salmonella-infected tumor cells[J].Cancer Res,2005,65(9):3 920
5Nishikawa H,Sato E,Briones G,et al.In vivo antigen delivery by a salmonella typhimurium type Ⅲ secretion system for therapeutic cancer vaccines[J].J Clin Invest,2006,116(7):1 946
6Zheng LM,Luo X,Feng M,et al.Tumor amplified protein expression therapy:Salmonella as a tumor-selective protein delivery vector[J].Oncol Res,2000,12(3):127
8Kasinskas RW,Forbes NS.Salmonella ty phimurium specifically chemotax and proliferate in heterogeneous tumor tissue In vitro[J].Biotechnol Bioeng,2006,94(4):710
9Zhao M,Yang M,Baranov E,et al.Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing salmonella typhimuriun[J].PNAS,2005,12(3):755
4Sekine K ,Tolda T, Saito M, et al. A new morphologilcally charactefized cell wall prepration (whole peptidoglycan) from bifidobacterium infantis with a high efficacy on the regression of an established tumor in mice. Cancer Res, 1985,45:1300.
5Reddy BS, Rivenson A. Inhibitory effect of bifidobacterium longum on colon,mammary and liver carcinogenesis induced by2 amino-3-methyeimidazo-4.5 f] quinotine, a food mutagen,Cancer Res 1993 53:3914.
6Sekine K, Ohta J, Onishi M, et al. Analysis of antitumor properties of effector cells stimulated with a cell wall preparation (WPG) of bifidobacterium infants. Biol Pharra Bull, 1995,18;148.
7Hockenbery D,Nunez G,Milliman C, et al. Bd-2 as an inner mitochondrial menbrane protein that blocks programmed cell death. Nature, 1990,384:334.
8Olival AN, Melliman CL, Korsmeyer SJ, et al Ecl-2 heterodimerizes in vivo with a conserved homolog,Bax,that accelerates programed cell death. Cell, 1993,74:609.
9Cui S. Reichner JS, Marco RB, et al. Activated routine macrophages induce apoptosis in tumor cells through nitric oxide dependent or independent mechanisms. Cancer Res, 1994,54:2462.
10Liu SC,Minton NP,Giaccia AJ.Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia necrosis[].Gene Therapy.2002
6Jemal A, Siegel R, Ward E, et al. Cancer statistics. 2007 [J]. CA Cancer J Clin, 2007, 57 (1): 43-66.
7Yu H, Jove R. The STAT sofcancer new molecular targets comeof age [J]. Nature Rev Cancer, 2004, 4 (1): 97- 105.
8TakedaK, Clausen BE, Kaisho T, et al. Enhanced' lhl activity and development of chronic enterocolitis in mice devoid of Star3 in macrophages and neutrophils[J].Immunity, 1999, 10 (1): 39-49.
9Elbashir SM , Lendeckel W , Tuschl T. RNA interference is mediated by 21-and 22-nucleotide RNAs [J]. Genes Dev, 2001, 15 (2): 188-200.
10Zhao XJ, Kong XB, Wang WH. Mass screening for prostate cancer is the best approach to early diagnosis and treatment of prostate cancer[J]. Nat J Androl, 2003, 9 (8): 563-565.
