缺血性脑卒中患者颈动脉粥样硬化相关因素分析

Analysis of correlation risk factors in patients with ischemic stroke

目的:探讨和分析缺血性脑卒中患者颈动脉粥样硬化的相关因素。方法:对缺血性脑卒中患者在发病后24小时内抽取血清测定C反应蛋白(C-reactiveprotein,CRP)水平,应用颈动脉彩色超声多普勒检查这些患者的颈动脉内膜-中层厚度(IMT),根据超声检查结果分为斑块组(IMT≥1.2mm)与无斑块组(IMT<1.2mm)。结果:颈动脉斑块组患者血CRP水平增高例数多于无斑块组(P<0.05)。该组患者的年龄明显高于正常组(P<0.01),伴有高血压及糖尿病的例数也明显高于无斑块组(P<0.01,P<0.05)。两组血白细胞计数比较差异无显著性(P>0.05)。结论:血清CRP水平增高对反映缺血性脑卒中患者颈动脉粥样硬化病变有显著临床意义。

Objective：To analyze the relationship between serum C-reactive protein （CRP） and carotid artery atherosclerosis in patients with ischemic stroke.Metheds：A total of 119 patients with ischemic stroke were included in is study.Serum level of CRP was measurd within 24 hours after onset of ischemic stroke. All patients were examined with carotid duplex ultrasonography scanning and divided into two groups：Mhnormal group（IMT〈l.2 ram） and M2：abnormal group（IMT≥1.2 mm）.Results：The number of patients with elevated CRP levels was increased in the M2 group （P〈0.05）.The patients with hypertension and diabetes mellitus in M2 group were significantly higher than those in MI group（P〈0.01,P〈0.05）.The mean age of M2 group was significantly older than that of MI group（P〈0.01）.Conclusion：Elevated CRP levels have a significant index for carotid artery atherosclerosis in patients with ischemic stroke.