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人端粒保护蛋白1研究现状

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出处 《胃肠病学》 2006年第9期558-560,共3页 Chinese Journal of Gastroenterology
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参考文献25

  • 1Baumann P,Cech TR.Pot1,the putative telomere endbinding protein in fission yeast and humans.Science,2001,292:1171~1175.
  • 2Baumann P,Podell E,Cech TR.Human Pot1 (protection of telomeres) protein:cytolocalization,gene structure,and alternative splicing.Mol Cell Biol,2002,22:8079~8087.
  • 3Loayza D,Parsons H,Donigian J,Hoke K,de Lange T.DNA binding features of human POT1:a nonamer 5'-TAGGGTTAG-3' minimal binding site,sequence specificity,and internal binding to multimeric sites.J Biol Chem,2004,279:13241 ~ 13248.
  • 4Ye JZ,Hockemeyer D,Krutchinsky AN,Loayza D,Hooper SM,Chait BT,de Lange T.POT1-interacting protein PIP1:a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.Genes Dev,2004,18:1649~1654.
  • 5Liu D,Safari A,O'Connor MS,Chan DW,Laegeler A,Qin J,Songyang Z.PTOP interacts with POT1 and regulates its localization to telomeres.Nat Cell Biol,2004,6:673~680.
  • 6Colgin LM,Baran K,Baumann P,Cech TR,Reddel RR.Human POT1 facilitates telomere elongation by telomerase.Curr Biol,2003,13:942~946.
  • 7Veldman T,Etheridge KT,Counter CM.Loss of hPot1 function leads to telomere instability and a cut-like phenotype.Curr Biol,2004,14:2264~2270.
  • 8Yang Q,Zheng YL,Harris CC.POT1 and TRF2 cooperate to maintain telomeric integrity.Mol Cell Biol,2005,25:1070~1080.
  • 9de Lange T.Shelterin:the protein complex that shapes and safeguards human telomeres.Genes Dev,2005,19:2100~2110.
  • 10Loayza D,De Lange T.POT1 as a terminal transducer of TRF1 telomere length control.Nature,2003,423:1013~1018.

二级参考文献8

  • 1Baumann P,Cech TR.Potl,the putative telomere end-binding protein in fission yeast and humans.Science,2001,292(5519):1171-1175.
  • 2Yang Q,Zheng YL,Harris CC.POT1 and TRF2 cooperate to maintain telomeric integrity.Mol Cell Biol,2005,25(3):1070-1080.
  • 3Kelleher C,Kurth I,Lingner J.Human protection of telomeres 1(POT1) is a negative regulator of telomerase activity in vitrol.Mol Cell Biol,2005,25(2):808-818.
  • 4Veldman T,Etheridge KT,Counter CM.Loss of hPot1 function leads to telomere instability and a cut-like phenotype.Curr Biol,2004,14 (24):2264-2270.
  • 5Koga H,Sakisaka S,Ohishi M,et al.Expression of cyclooxygenase-2 in human hepatocellular carcinoma:relevance to tumor dedifferentiation.Hepatolgoy,1999,29 (3):688-696.
  • 6Kondo T,Oue N,Yoshida K,et al.Expression of POT1 is associated with tumor stage and telomere length in gastric carcinoma.Cancer Res,2004,64(2):523-529.
  • 7Rudolph KL,Millard M,Bosenberg MW,et al.Telomere dysfunction and evolution of intestinal carcinoma in mice and humans.Nat Genet,2001,28(2):155-159.
  • 8Blackburn EH.Switching and signaling at the telomere.Cell,2001,106(6):661-673.

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