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T138067及其衍生物在肿瘤治疗中的应用 被引量：1

T138067 and its derivaties in tumor
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摘要 T138067是一类在磺胺结构基础上合成的新化合物,由于其独特的以微管为作用靶点,已成为抗肿瘤治疗研究的热点之一。现综述其抗肿瘤作用机制、应用研究、抗耐药性等方面的研究进展。 T138067 is a new compound synthesized on the basis of sulfonamide drugs. It becomes one of the hotspots in the anti-tumor drugs study because of its binding to microtubule uniquely. This paper reviews research advancement on the anti-tumor mechanism, anti-muhidrug resistance of T138067 and its clinic research.
作者 周东勋 胡和平
机构地区 第二军医大学东方肝胆外科医院综合二科
出处 《国际肿瘤学杂志》 CAS 2006年第9期650-653,共4页 Journal of International Oncology
关键词 微管 衍生物 抗药性 肿瘤 Microtubule Derivative Drug resistance, neoplasm
分类号 R730.5 [医药卫生—肿瘤]
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参考文献18

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同被引文献22

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国际肿瘤学杂志
2006年 第9期

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