摘要
采用肝硬变大鼠模型，观察了复方丹参对肝缺血再灌注损伤的防护作用，结果显示：复方丹参可显著减少损伤后的血清ＡＩＴ（谷丙转氨酸）、ＬＤＨ（乳酸脱氢酶）水平，减少肝组织过氧化脂质的产生，减轻肝细胞的病理性损伤。表明复方丹参可增强肝硬变肝细胞的抗氧化能力，对其缺血再灌注损伤起到保护作用。
The protective effects of salvia miltiorrhiza on liver ischemia reperfusion injury were studied in cirrhotic rat models induced by carbontetrachloride. Serum ALT and LDH levels and amount of hepatic lipid peroxides were significantly increased after liver ischemia reperfusion injury; the increment was significantly inhibited by salvia miltiorrhiza treatment. The hepatocellular injury in light microscopy was much slight in the treated group. These results suggested that salvia miltiorrhiza could protect the cirrhotic liver against ischemia reperfusion injury.
出处
《徐州医学院学报》
CAS
1996年第3期265-267,共3页
Acta Academiae Medicinae Xuzhou
基金
江苏省教委自然科学基金
