支气管肺泡灌洗在严重肺部感染中的治疗作用

Effects of bronchoalveolar lavage in patients with severe lung infection

目的探讨支气管肺泡灌洗(BAL)对严重肺部感染的临床疗效。方法对65例原发或继发严重肺部感染病例,进行随机对照研究,32例给予常规治疗(对照组);33例在正常治疗的基础上加用BAL治疗(BAL组)。分别于治疗后3、7及14d判断临床疗效以及评估BAL治疗时的并发症和不良反应。结论对照组在治疗后3、7、14 d显效率分别为34.4%、40.6%、43.8%,BAL组显效率分别为51.5%、66.7%、69.7%,两组间疗效差异有显著性(P<0.01)。BAL治疗组无1例严重并发症。结论BAL治疗严重肺部感染疗效显著,安全可靠,简便易行,值得临床推广。

Objective To explore the therapy effect of brenchoalveolar lavage （BAL） on severe lung infections. Methods Sixtyfive cases with primary or secondary severe lung infections were randomly divided into control group （32 cases） and BAL group （33 cases） and the clinical effects were estimated in 3 days, 7 days, and 14 days. Results The cure rates in control group were 34. 4%, 40. 6%and 43.8%and they were 51.5%, 66. 7% ,69. 7% in BAL group in 3 days, 7 days and 14 days. So the cure rate in BAL group is better than control group significantly （P 〈 0. 01 ）. Severe complication were not been found. Conclusion The treatment by BAL is effective, safe, reliable, convenient and worth promoting on severe lung infections.