肝动脉化疗栓塞与灌注药物对肝癌疗效的比较

Comparative study on therapeutic effects of hepatic artery chemoembolization and infusion chemotherapy for hepatocellular carcinoma

报告５０例不能手术切除的中、晚期肝癌经肝动脉化疗栓塞（ＨＡＣＥ）或灌注药物（ＨＡＩＣ）治疗的前瞻性临床观察比较结果，ＨＡＣＥ组２３例（６１次）和ＨＡＩＣ组２７例（７２次）治疗均成功，前者疗效（包括有效率、术后生存率）较后者为优（Ｐ＜０．０１），且两组副作用相仿。揭示ＨＡＣＥ是治疗肝癌更为有效的手段，并也适用于肝癌合并门脉瘤栓时。

We report here a comparative study in which 50 patients with unresectable liver cancer were treated by hepatic artery chemoembolization (HACE) or hepatic artery infusion chemotherapy (HAIC).Twenty-three cases(61 treatments)of the HACE group and 27 cases (72 treatments) of the HAIC group were treated successfully. The therapeutic effects (including the remission rate and survival rate)in HACE were better than those in HAIC(P<0.01),and the adverse effects of both groups were similar .These results suggested that HACE appeared supetior to HAIC on primary hepatic carcinoma treatment,and might be used in the patients with portal vein thrombosis.