老年与成年猕猴中医指标及血清微量元素比较

Comprison on Targets of TCM and Trace Elements Between the aged and the adult of macaque as experimental Animals

研究观测了３４１只成年猕猴及１３８只老年猕猴的中医指标及两组各１０只的毛、血清微量元素，比较结果为：老年组舌、口津、五官、皮色、皮质、形体等呈现病理表现增多（Ｐ＜０．０１或Ｐ＜０．０５），趋于老化及衰退，明显出现虚衰（肾虚、脾虚、气虚、阳虚）．毛、血清微量元素比较，老年组锌降低（Ｐ＜０．０５），血清钙、镁降低（Ｐ＜０．０１），说明微量元素值可作为辨证时的参考依据。认为：（１）中医指标可用于猕猴辨证，尤其实用于中医药实验研究。（２）老年猕猴是中医药老年医学最佳实验动物。（３）猕猴年龄段区别是实验中必须注意的问题。

Observation and detennination of the targets of TCM of both 341 adult macaque and138 aged macaque and the trace elements in hairs and serum were described in the paper from a research Theresults from the compari son shoued: 1. The tangue,saliva, five sense organs,skin colour,skin mass andmorphology etc. show the increase of pathological phenomena(P<0.01 or P< 0.05),the tread of ageing anddecline and obvious weakness-derlciency of vital function and essence of te kidney,deficiency and weaknessof fumctional activities or essence of the spleen,deficiency of vital function and essence of the body.2.Com-parison in trace elements in hairs and serum:the aged group has decrease of Zn(P<0.05),Ca and Mg(P< 0.01)in serum. It shows that the data of trace elements could be become as references of analysingTCM Syndrom;Conclusion:1.The targets of TCM could be used in analysing syndrom of macaque,specially, suitable to the experimental research of TCM and Medica Materia.2. The aged macaque is anoptimum experimental animal for the presbyatrics of TCM.3.Deferenee of the age range of macaque shouldbe noticed in the experiment.