卵巢交界性肿瘤32例临床分析

The Clinical Analysis of 32 Cases with Borderline Ovarian Tumors

目的：探讨卵巢交界性肿瘤（BOT）的临床特征和治疗方法。方法：回顾分析20年问收治的BOT32例。年龄18～71岁，平均38岁。结果：病理类型，浆液性20例（62．50％），黏液性12例（37．50％）；手术-病理分期，Ⅰ期22例（68．75％），Ⅱ期6例（18．75％），Ⅲ期4例（12．50％）。浆液性肿瘤患者18—71岁，平均41．3岁，黏液性肿瘤患者18—64岁，平均年龄34．7岁。术后复发2例（6．25％），2例Ⅲ期患者和1例Ⅱ期患者合并血性腹水术后5年内死亡，1例Ⅲ期患者术后5．5年死亡，另1例Ⅲ期患者现已术后2年，发生肝转移仍存活，2例Ⅰ期患者分别于术后12年、17年自然死亡。患者5年、10年、20年的生存率分别为90．62％、86．21％、84．00％。结论：浆液性肿瘤所占比例高于黏液性肿瘤，但黏液性肿瘤较浆液性肿瘤患病年龄小；手术是治疗BOT的主要方法，应力求将肿瘤完全切尽；经多因素分析，临床分期是影响预后的主要因素。

Objective： To study the clinical features and management of Borderline Ovarian Tumors （BOT）. Methods： 32 cases with Borderline Ovarian Tumors are retrospectively analyzed. The age of serious tumor is from 18 to 71, and the average age is 41.3. The age of mucous tumor is from 18 to 64, and the average age is 34. 7. Total mean age is 38. Pathological type includes 20 cases （62. 5% ） of serious tumor and 12 cases （ 37. 5% ） of mucous tumor. Surgery - pathology stage includes Ⅰ ： 22 cases （ 68.8% ） , Ⅱ ： 6 cases （ 18. 9% ） and Ⅲ ： 4 cases （ 12. 5% ） . Results： 1 case （3. 1% ） relapsed. 2 cases of stageⅢ and 1 case of stage Ⅱ with blood water died of disease postoperation in 5 years, 1case of stage Ⅲ died of disease postoperation. Another 1case of stage Ⅲ has found transmit of liver and still live after 2 years postoperation. 2 cases of stage I died of natural disease after 12 and 17 years of surgery respectively. The 5, 10, 20 -year survival is 90. 6% , 86. 2%, 84. 0% respectively. Conclusion： Proportion of serous tumor is higher than that of mucous tumor. The age of mucous tumor is younger than that serous tumor. Surgery is the main treatment for BOT, unless any residual disease is expected. Cox regression model analysis shows the stage is the main prognosis factor of BOT.