水中取代水杨醛和氰乙酸酯的反应研究

Study on the Reaction of Substituted Salicylaldehydes with Cyanoacetate in Water

以水杨醛和氰乙酸酯为原料,以水为溶剂,以三乙基苄基氯化铵为催化剂在不同的反应温度下合成了两个系列的色烯衍生物,该方法具有反应条件温和、立体选择性好、产率高等优点.

Two series of chromene derivatives were synthesized from the substituted salicylaldehyde with cyanoacetate in water at two reaction temperatures catalyzed by triethylbenzyl ammonium chloride （TE- BAC）. Such method has the advantages of easier work-up, milder reaction conditions, better yields than other synthetic methods.