化学溶核术治疗腰椎间盘突出症652例分析

Analysis of 652 of Collagenase Injection to Treat the Herniated Lumbar Intervertebral Disc

目的 探讨化学溶核术治疗腰椎间盘突出症的临床效果。方法 对1997-2004年6月我院的652例腰椎间盘突出患者在X线透视下采用12号穿刺针穿刺到病变椎间隙，注入600—1200万单位胶原酶。术后应用抗生索．绝对卧床1周。结果 术后平均随访12个月．优良率达81％。结论 化学溶核术是治疗腰椎间盘突出症的一种微创、有效的治疗方法，在基层医院有推广价值。

Objective To evaluate the effect of collagenase injection on the treatment of herniated lumbar intervertebral disc. Methods The study was a retrospective review of 652 records of the patients who were admitted to PLA 11th Hospital in Yining, Xinjiang with the diagnosis of herniated lumbar disc spine between 1997 and 2004. All of the patients underwent puncture into intervertebral cranny with a size 12 needle under the X-ray and were injected 6 -12 million IU of collagenase. After the operation, we ordered the patients to keep the bed one week. Results There were about 81% of the patients whose nerve function recovered favourably. Conclusion It is little traumatic and very effective to treat the herniated lumbar disc spine with collagenase injection and the method is worth extending among basic or grass-roots hospitals.